![]() A positive anti-HBc (or HBcAb) test result requires talking to your health care provider for a complete explanation of your hepatitis B status. This test can only be fully understood by knowing the results of the first two tests (HBsAg and anti-HBs). The core antibody does not provide any protection against the hepatitis B virus (unlike the surface antibody described above). anti-HBc or HBcAb (Hepatitis B core antibody) - A "positive" or "reactive" anti-HBc (or HBcAb) test result indicates a past or current hepatitis B infection.You are not infected and cannot spread hepatitis B to others. Tissue cross-reactivity assay is a standard method based on immunohistochemistry, required prior to phase I human studies for therapeutic antibodies. Choosing appropriate antibodies is the most direct. A positive anti-HBs (or HBsAb) test result means you are “immune” and protected against the hepatitis B virus and cannot be infected. Testing the cross-reactivity of antibodies with closely related antigens is an important validation test. This test is not routinely included in blood bank screenings. This protection can be the result of receiving the hepatitis B vaccine or successfully recovering from a past hepatitis B infection. anti-HBs or HBsAb (Hepatitis B surface antibody) - A "positive" or "reactive" anti-HBs (or HBsAb) test result indicates that a person is protected against the hepatitis B virus.A positive HBsAg test result means that you are infected and can spread the hepatitis B virus to others through your blood. If a person tests “positive,” then further testing is needed to determine if this is a new “acute” infection or a “chronic” hepatitis B infection. This test can detect the actual presence of the hepatitis B virus (called the “surface antigen”) in your blood. HBsAg (Hepatitis B surface antigen) - A "positive" or "reactive" HBsAg test result means that the person is infected with hepatitis B. After the plates were washed of secondary antibody, TMB substrate was added, allowed to incubate at room temperature for 30 min, and then the reaction was stopped using 0.18 molar sulfuric acid.Important factors that affect Cross-reactivity are the specimen type, test performed, reagents utilized, and concentration of substances in the specimen being tested. Below is an explanation of the 3-part “Hepatitis B Panel” of blood test results. Immunoassay drug testing is where Cross-reactivity comes into play most often. All three test results are needed to fully understand whether a person is infected or not. Only one sample of blood is needed for a hepatitis B blood test, but the “Hepatitis B Panel” includes three parts. Hepatitis B Blood Tests The “Hepatitis B Panel” of Blood Tests
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